Publication
Abstract:Cancer remains a leading cause of mortality worldwide, with existing treatments often being costly and accompanied by adverse effects. This study investigated the antiangiogenic activity of Alokon (Broussonetia luzonica) flower extract as a potential natural alternative for inhibiting blood vessel formation critical to tumor growth. Using the Chick Chorioallantoic Membrane (CAM) assay, the study evaluated blood vessel inhibition across six treatment groups: distilled water (negative control), Quercetin (positive control), and four extract concentrations (25%, 50%, 75%, and 100%). Results demonstrated that Alokon extract exhibited a dose-dependent inhibition of angiogenesis, with the 100% concentration achieving comparable efficacy to Quercetin (27.87% and 29.60% inhibition, respectively). Statistical analyses, including ANOVA and Scheffé test, confirmed significant differences between treatment groups, highlighting the extract’s potential as a cost-effective antiangiogenic agent. These findings highlight the value of Alokon flower extract in developing accessible cancer therapies, warranting further exploration into its bioactive compounds and therapeutic applications.
Keywords:Antiangiogenic Activity, Alokon, Chorioallantoic Membrane, IKOSA
On-going
- Feasibility Study on the Offering of MS Biology in UNP ( E-22-23-c43)
- Marine Macrobenthic Algae of the Coastal of Ilocos Sur, Philippines (AFNR-22-23-C11)
- Women in the Codium Industry: A Comparative Analysis of their Roles and Contributions (AMRRDC-25-1)
- Development of Gracilaria sp. – Enriched Kimchi: A functional and Sustainable Food Innovation (AMRRDC-25-2)
- Species Diversity and Composition of Mangroves in Ilocos Sur, Philippines (AFNR-22-23-c11)
- Development and Acceptability of Seaweed-Crisps (AMRRDC24-5)
Awards
- INTERNATIONAL
- International Quality Award- Diamond Award- Oral Research Presentation- 2nd International Conference on Multidisciplinary Research I October 21-22, 2011 I Bacolod City
- International Quality Award- Best PowerPoint- 2nd International Conference on Multidisciplinary Research I October 21-22, 2011 I Bacolod City
- NATIONAL
- 2nd Place Winner Research Poster Category – Research Poster Presenter – Philippine Science Consortium
- 2nd Best Presentation DOST- TECHGROW I May 16, 2025
- LOCAL
- 4th Place Award (Oral Presentation), National Multidisciplinary Research Conference 2013 I May 22-24, 2013 I UNP, Vigan City
- 3rd place poster presentation, 28th Regional Symposium on R & D Highlights I November 7-8, 2016
- Faculty of the year I 2025 I UNP, Vigan City
Presentation
- Growth and Production of Oyster Mushroom Using Peanut as Substrate Supplement (2024)
- Growth Performance of Gracilaria sp. (Kawkawayan) using the Raft Culture Method (2024)
Citations
Sorry, but there’s nothing here.
IP Registration
Sorry, but there’s nothing here.